Infertility is increasing day by day especially for Indian couples , and choosing the right fertility treatment is a crucial decision for couples trying to conceive. Intrauterine Insemination (IUI) and In Vitro Fertilization (IVF) are two of the most common assisted reproductive techniques available. But which one is the best option for you?
Both treatments offer hope, but they differ in their process, success rates, costs, and ideal candidates. In this this blog we have covered IUI vs. IVF in detail, helping you understand their differences and make an informed decision.
What is IUI? (Intrauterine Insemination)
IUI, or Intrauterine Insemination, is a fertility treatment where specially prepared sperm is directly placed into the uterus during ovulation. This method increases the chances of sperm reaching the egg, making fertilization more likely.
How IUI Works
The IUI procedure follows these key steps
- Ovulation Tracking: The doctor monitors the woman’s ovulation cycle using ultrasound or ovulation predictor kits.
- Sperm Preparation: A semen sample is collected from the male partner or a donor. The sperm is then “washed” to remove impurities and improve motility.
- Sperm Insertion: The washed sperm is inserted into the uterus through a thin catheter.
- Waiting for Fertilization: If the sperm successfully fertilizes the egg, implantation occurs, leading to pregnancy.
IUI : Best For Whom ?
IUI is generally recommended for:
- Couples with unexplained infertility
- Women with mild endometriosis
- Men with mild sperm abnormalities (low motility or low sperm count)
- Women with cervical mucus issues that prevent sperm from reaching the egg
- Same-sex couples or single women using donor sperm
Also Read : Low Sperm Count Treatment for Male Infertility
Success Rates of IUI
Success rates for IUI depend on several factors, including age, fertility diagnosis, and sperm quality. Here’s an estimated breakdown:
| Age Group | IUI Success Rate per Cycle |
|---|---|
| Under 35 | 10% – 20% |
| 35-40 | 8% – 15% |
| Over 40 | 3% – 8% |
Multiple cycles of IUI may be needed before achieving pregnancy. Typically, if IUI does not result in pregnancy after 3-6 cycles, doctors may recommend IVF as the next step.
Advantages of IUI
✔ Less invasive than IVF
✔More affordable compared to IVF
✔Simple and quick procedure (can be done in a doctor’s office)
✔Minimal medication required
Limitations of IUI
– Lower success rates compared to IVF
– Not effective for severe male infertility
– Higher chances of failure in older women
What is IVF? (In Vitro Fertilization)
IVF, or In Vitro Fertilization, is an advanced fertility treatment where eggs and sperm are combined outside the body in a lab. Once fertilization occurs, the embryo is transferred into the uterus for implantation.
How IVF Works
The IVF process involves multiple steps and is more complex than IUI. Here’s a step-by-step breakdown:
- Ovarian Stimulation: Fertility medications stimulate the ovaries to produce multiple eggs instead of just one.
- Egg Retrieval: Mature eggs are collected using a minor surgical procedure called follicular aspiration.
- Sperm Collection & Fertilization: A semen sample is collected, and sperm is combined with the eggs in a laboratory for fertilization.
- Embryo Culture: The fertilized eggs develop into embryos over 3-5 days in a controlled environment.
- Embryo Transfer: The best-quality embryo(s) are selected and transferred into the uterus.
- Pregnancy Test: After 10-14 days, a blood test confirms whether implantation was successful.
IVF : Best For Whom ?
IVF is generally recommended for:
- Women with blocked or damaged fallopian tubes
- Couples with severe male infertility (low sperm count, poor motility, or abnormal morphology)
- Women with endometriosis or ovulation disorders
- Couples who have failed multiple IUI cycles
- Individuals with genetic disorders who need embryo screening (PGT)
- Women opting for fertility preservation through egg freezing
Success Rates of IVF
The success of IVF depends on multiple factors, including age, egg quality, and underlying fertility issues. Below is an estimated success rate by age:
| Age Group | IVF Success Rate per Cycle |
|---|---|
| Under 35 | 40% – 50% |
| 35-37 | 35% – 45% |
| 38-40 | 25% – 35% |
| Over 40 | 10% – 20% |
Success rates for IVF are significantly higher than IUI, especially for women over 35. However, multiple cycles may still be required.
Advantages of IVF
✔ Higher success rates compared to IUI
✔ Can bypass fallopian tube issues
✔ Allows for genetic testing of embryos before transfer
✔Option to freeze embryos for future use
✔ More control over embryo selection
Limitations of IVF
–Expensive compared to IUI
–More invasive with multiple procedures involved
–Higher risk of multiple pregnancies if multiple embryos are transferred
–Potential side effects from fertility medications
IUI vs. IVF – Key Differences and How to Choose the Right Option
Deciding between IUI and IVF depends on several factors, including age, fertility diagnosis, financial considerations, and personal preferences.
Below is a comparison of both treatments to help you determine the best option.
Key Differences Between IUI and IVF
| Factor | IUI (Intrauterine Insemination) | IVF (In Vitro Fertilization) |
|---|---|---|
| Procedure | Sperm is inserted directly into the uterus | Eggs and sperm are fertilized in a lab, then the embryo is transferred |
| Invasiveness | Minimally invasive (no surgery required) | More invasive (requires egg retrieval and embryo transfer) |
| Cost | Lower cost per cycle | Higher cost due to medications, lab procedures, and multiple steps |
| Success Rate | 10-20% per cycle (lower in older women) | 40-50% per cycle for women under 35 (higher success rates) |
| Time Required | Quick procedure, no downtime | Process takes several weeks per cycle |
| Best for | Unexplained infertility, mild male factor infertility, cervical mucus issues, single women, or same-sex couples using donor sperm | Severe infertility, blocked fallopian tubes, endometriosis, ovulation disorders, genetic conditions, multiple failed IUI attempts |
| Risk of Multiple Births | Higher chance due to multiple eggs released naturally | Can be controlled by transferring a single embryo |
How to Choose Between IUI and IVF
The best fertility treatment depends on several factors, including diagnosis, age, and treatment goals. Below are some important considerations:
1. Your Age
- Under 35: IUI may be a good first step if you have unexplained infertility or mild male factor issues. However, if IUI fails after a few cycles, IVF is the next logical step.
- Over 35: IVF is often recommended since egg quality declines with age. Waiting too long with IUI may reduce the overall chances of pregnancy.
2. The Cause of Infertility
- If infertility is unexplained or due to mild male factor issues, IUI is usually the first treatment option.
- If there are blocked fallopian tubes, severe male infertility, or genetic conditions, IVF is a better choice.
3. Budget & Financial Considerations
- IUI is less expensive per cycle, making it a preferred option for couples on a budget.
- IVF, although costly, has higher success rates and may be more cost-effective in the long run by reducing the number of treatment cycles needed.
4. Time Sensitivity
- If you are looking for a quicker, less invasive solution, IUI is the first-line treatment.
- If time is a concern (especially for older women or those with low ovarian reserve), IVF is the faster and more effective route.
5. Success Rate Expectations
- If IUI fails after 3-6 cycles, IVF should be considered for better chances of pregnancy.
- If success rates are a priority and cost isn’t a major concern, IVF provides a higher probability of conception.
IVF and IUI Cost in India
The cost of IUI and IVF in India varies depending on factors like clinic reputation, city, medications, and additional procedures. Here’s an approximate breakdown:
| Treatment | Cost Range in India (INR) | Cost in Chennai (Approx.) |
|---|---|---|
| IUI (Intrauterine Insemination) | ₹10,000 – ₹25,000 per cycle | ₹12,000 – ₹20,000 per cycle |
| IVF (In Vitro Fertilization) | ₹1,00,000 – ₹2,50,000 per cycle | ₹1,20,000 – ₹2,00,000 per cycle |
| ICSI (Advanced IVF with Sperm Injection) | ₹1,50,000 – ₹3,00,000 per cycle | ₹1,80,000 – ₹2,50,000 per cycle |
| Donor Egg IVF | ₹2,00,000 – ₹4,00,000 | ₹2,50,000 – ₹3,50,000 |
| Embryo Freezing | ₹25,000 – ₹50,000 per year | ₹30,000 – ₹45,000 per year |
Note: Prices may vary based on medications, hospital facilities, and additional tests. It’s best to consult a nearest hospital with you for an accurate cost estimate.
Final Thoughts: Which One is Right for You?
There is no one-size-fits-all answer when it comes to IUI vs. IVF. Some couples may conceive through IUI alone, while others may need to move to IVF for better results. Consulting with a fertility specialist can help tailor the best approach based on your medical history, test results, and personal preferences.
Both treatments have helped millions of couples achieve parenthood. Whether you start with IUI or opt for IVF, the ultimate goal remains the same—a healthy pregnancy and a happy family.
If you’re looking for a trusted fertility hospital in Chennai, Nandhini-Pearl Hospital provides advanced fertility treatments, expert specialists, and compassionate care to support your journey to parenthood. Whether you’re considering IUI, IVF, or other fertility solutions, our team is here to guide you every step of the way.
📞 Book a Consultation Today and take the first step toward making your dream of parenthood a reality!
Visit Nandhini-Pearl Hospital for more details.